Versions prior to SEP 11.5 are having problems removing and cleaning up old definition files. These versions are not properly deleting the old definition and temp files. If you are experiencing low disk space on your SEPM server then you can follow the below Symantec Support articles to help free up space until you’re able to do the upgrade to SEP 11.5+.
http://service1.symantec.com/SUPPORT/ent-security.nsf/docid/2010010617161948?Open&seg=ent
http://service1.symantec.com/support/ent-security.nsf/docid/2007123111551948