If you are running Trend Micro on a Terminal Server, you should consider removing the systray process for monitoring Trend Micro on each user account.

REMOVE INI ENTRIES
notepad C:Program FilesTrend MicroClient Server Security Agentofcscan.ini
search for NT_RUN_KEY_FILE_NAME=pccntmon.exe and change to
NT_RUN_KEY_FILE_NAME=

NT_RUN_KEY_FILE_NAME=pccntmon.exe Removed by Admin

search for NT_RUN_KEY=OfficeScanNT Monitor and change to
NT_RUN_KEY=

NT_RUN_KEY=OfficeScanNT Monitor Removed by Admin

REMOVE REGISTRY ENTRY
regedt32
Navigate to HKEY_LOCAL_MACHINESoftwareMicrosoftWindowsCurrentVersionRun
remove OfficeScanNT Monitor

Then reboot the server during the next change window or just wait for staff to logoff and login at a future point to allow the change to progress on a per user basis.

Hope this helps!
Charley